We focus on a ~70 km across-strike transect from the core of the Sebago pluton (ca. 293 Ma) SE into the highest strain portion of the NSZS in its deepest regional exposure near Brunswick. New mapping of the pluton, previously considered the largest exposed in New England (>1600 km2), shows a clearly separate central body of homogeneous granite (<400 km2) derived from Avalon-like sources. The body is flanked by a migmatite domain permeated by smaller bodies of more geochemically heterogeneous granite (the Sebago migmatite domain). Extant geochemical data are consistent with derivation of these subconcordant granites from materials similar to their host metasedimentary rocks (Central Maine belt source). In the migmatite domain, deformational fabrics in amphibolite facies country rocks are relatively variable in orientation. However, the area SE of the pluton, adjacent to the NSZS, contains penetratively parallel structures at all scales, including fabrics in metamorphic rocks, migmatites and concordant granite sheets. Fabrics are consistently NE-SW-striking- and steeply to moderately SE-dipping, similar in orientation to those in the NSZS suggesting control of granite ascent by deformation in the NSZS. Within this well-constrained structural framework, geochemical and geochronological studies can provide meaningful tectonic constraints.